QF-PCR Rapid Diagnosis of Trisomy 21, 18, 13 and Sex Chomosomes Aneuploidies
Copyright Aneufast™ QF-PCR 2006
Product Overview QF-PCR
Aneufast is a Quantitative Fluorescent PCR (QF-PCR) Kit designed to perform rapid prenatal diagnosis of chromosomes 21, 18, 13, X and Y aneuploidies.
..............................................................................................................
The Aneufast™ QF-PCR Kit contains six multiplex marker sets of short tandem repeats (STRs) that can be used for amplification of selected microsatellites and the Amelogenin-SRY.
..............................................................................................................
Aneufast™ is intended to be used to amplify DNA extracted from fresh prenatal samples such as Amniotic Fluids, CVSs or fetal blood. It can also be used to analyse neonatal and adult blood or tissue samples.
..............................................................................................................
Two multiplex QF-PCR sets (S1and S2) are used to perform initial Aneuploidy Screening and the assays are designed to be analysed in a single electrophoresis; In addition, there are four chromosome- specific marker sets (M21, M13, M18 and MXY). They may be used as back-ups in case all the markers on S1 and S2 are non-informative (homozygous). However, they may also be applied individually for the diagnosis of trisomy 13, 18, 21 and sex chromosome aneuploidies, respectively.
..............................................................................................................
Main Features
- Sample to Result in less than 4 hours
- IVD/CE certified under 98/79/EC. Manufactured to ISO 9001:2000 ISO13485:2003
- Ready to run mix, just add DNA
- Extra markers for 21, 18, 13, X, Y are included with each kit
- Optimised to work on all Applied Biosystems sequencers
- Five-Dye DNA Fragment Analysis
Most markers included in Aneufast™ have been extensively validated and applied on over 25.000 clinical specimens.
